Review article: the Molecular Adsorbents Recirculating System (MARS) in liver failure
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چکیده
منابع مشابه
Equipment review: The molecular adsorbents recirculating system (MARS®)
The molecular adsorbents recirculating system (MARS) is a form of artificial liver support that has the potential to remove substantial quantities of albumin-bound toxins that have been postulated to contribute to the pathogenesis of liver cell damage, haemodynamic instability and multi-organ failure in patients with acute liver failure (ALF) and acute-on-chronic liver failure (AoCLF). These to...
متن کاملMolecular adsorbent recirculating system (MARS).
INTRODUCTION Molecular adsorbent recirculating system (MARS) for albumin liver dialysis has been used as a bridge to liver transplantation in patients with fulminant hepatic failure (FHF). This review examines the available data on its clinical use, its technical aspects and present gaps in knowledge. METHODS Peer-reviewed journals and monographs on the subject were covered. RESULTS FHF is ...
متن کاملAcute liver failure and the Molecular Adsorbents Recirculating System: early experience in a tertiary care hospital in Mexico City.
Acute liver failure is a clinical condition associated with high mortality despite recent technological advances. Supportive devices such as the Molecular Adsorbents Recirculating System (MARS) provide therapeutic strategies to add time to find an organ for orthotopic liver transplantation or to allow the native liver to recover sufficiently to make transplantation unnecessary. In this series o...
متن کاملAlbumin dialysis with molecular adsorbent recirculating system (MARS) for the treatment of hepatic encephalopathy in liver failure.
Acute, acute-on-chronic and chronic liver diseases are major health issues worldwide, and most cases end with the need for liver transplantation. Up to 90% of the patients die waiting for an organ to be transplanted. Hepatic encephalopathy is a common neuropsychiatric syndrome that usually accompanies liver failure and impacts greatly on the quality of life. The molecular adsorbent recirculatin...
متن کاملExtracorporeal liver support-albumin dialysis with the Molecular Adsorbent Recirculating System (MARS).
Extracorporeal liver support has been a much studied topic throughout the last 50 years. Albumin dialysis as a therapeutic option for patients with acute liver failure or acute decompensation of chronic liver disease was introduced in the mid-nineties. The Molecular Adsorbent Recirculating System (MARS) is based on the concept of albumin dialysis and allows for the removal of protein-bound as w...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2002
ISSN: 0269-2813
DOI: 10.1046/j.1365-2036.16.s5.5.x